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ey0018.4-12 | New Perspectives | ESPEYB18

4.12. DNA methylation profiling and genomic analysis in 20 children with short stature who were born small for gestational age

S Peeters , K Declerck , M Thomas , E Boudin , D Beckers , O Chivu , C Heinrichs , K Devriendt , F de Zegher , Hul Van , Vanden Wim , V Berghe , J De Schepper , R Rooman , G Mortier

J Clin Endocrinol Metab. 2020;105(2):dgaa465. doi: 10.1210/clinem/dgaa465. PMID: 32685970This study aimed to identify potential (epi)genetic causes of short stature in 20 SGA children (13 boys; 7 girls) treated with rhGH. Exome sequencing, single-nucleotide polymorphism (SNP) array (both performed in the whole cohort) and genome-wide methylation analysis (performed in a random subset of 10 ...

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ey0017.3-4 | Thyroid and pregnancy | ESPEYB17

3.4. Association of exposure to ambient air pollution with thyroid function during pregnancy

A Ghassabian , L Pierotti , M Basterrechea , L Chatzi , M Estarlich , A Fernandez-Somoano , AF Fleisch , DR Gold , J Julvez , P Karakosta , A Lertxundi , MJ Lopez-Espinosa , TA Mulder , TIM Korevaar , E Oken , RP Peeters , S Rifas-Shiman , E Stephanou , A Tardon , H Tiemeier , M Vrijheid , TGM Vrijkotte , J Sunyer , M Guxens

To read the full abstract: JAMA Netw Open. 2019;2:e1912902.Air pollution has recently been associated with maternal thyroxine levels during mid gestation in a large single cohort study [1]. No data exist so far on the association of exposure to specific markers of residential air pollution during the first trimester, when neurodevelopment of the embryo is exclusively dependent on transplacental passage of maternal thyroxine.<p class="abstext...

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ESPE Yearbook of Paediatric Endocrinology

4.12. DNA methylation profiling and genomic analysis in 20 children with short stature who were born small for gestational age

3.4. Association of exposure to ambient air pollution with thyroid function during pregnancy

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