ISSN 1662-4009 (online)

ey0016.7-14 | Clinical Guidance | ESPEYB16

7.14. Pituitary deficiency and precocious puberty after childhood severe traumatic brain injury: a long-term follow-up prospective study

Y Dassa , H Crosnier , M Chevignard , M Viaud , C Personnier , I Flechtner , P Meyer , S Puget , N Boddaert , S Breton , M Polak

To read the full abstract: Eur J Endocrinol. 2019 May 1;180(5):281–290.This longitudinal prospective study of 61 children with a 5-10 years follow-up post severe traumatic brain injury evaluates the prevalence of pituitary deficiency and precocious puberty.In children, retrospective and prospective studies report variable rates of hypothyroidism...

ey0021.1-13 | New Treatments and Hopes | ESPEYB21

1.13. Long-term weight gain in children with craniopharyngioma

S Rovani , V Butler , D Samara-Boustani , G Pinto , L Gonzalez-Briceno , Quoc A Nguyen , G Vermillac , A Stoupa , A Besancon , J Beltrand , C Thalassinos , I Flechtner , Y Dassa , M Viaud , MB Arrom-Branas , N Boddaert , S Puget , T Blauwblomme , C Alapetite , S Bolle , F Doz , J Grill , C Dufour , F Bourdeaut , S Abbou , L Guerrini-Rousseau , A Leruste , K Beccaria , M Polak , D Kariyawasam

Brief Summary: This single-centre retrospective cohort study offers valuable insights into the trajectory of weight gain in a paediatric craniopharyngioma cohort over a mean follow-up period of 10.4 years, reinforcing the necessity for targeted interventions to address this issue.Craniopharyngioma poses a substantial clinical challenge in paediatric patients, primarily due to the risk of hypothalamic involvement. A particularly severe long-term consequen...

ey0021.9-13 | Growth Problems in Cancer Survivors | ESPEYB21

9.13. GH and childhood-onset craniopharyngioma: when to initiate GH replacement therapy?

A Nguyen Quoc , K Beccaria , Briceno L Gonzalez , G Pinto , D Samara-Boustani , A Stoupa , J Beltrand , A Besancon , C Thalassinos , S Puget , T Blauwblomme , C Alapetite , S Bolle , F Doz , J Grill , C Dufour , F Bourdeaut , S Abbou , L Guerrini-Rousseau , A Leruste , S Brabant , I Cavadias , M Viaud , N Boddaert , M Polak , D Kariyawasam

Brief Summary: This retrospective, observational, single centre study compared the risk of tumor progression or recurrence in 71 patients with childhood-onset craniopharyngioma (CP) who started GH replacement therapy (GHRT) with different latency from the end of tumor treatment.GHRT latency was defined as the time from end of CP treatment (last debulking procedure or radiotherapy, or from CP diagnosis for the 5 patients without any debulking procedure or...