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ey0020.10-7 | New Drugs for Children with T2DM | ESPEYB20

10.7. Maternal diabetes in youth-onset type 2 diabetes is associated with progressive dysglycemia and risk of complications

RD Shah , SD Chernausek , L El Ghormli , ME Geffner , J Keady , MM Kelsey , R Farrell , B Tesfaldet , JB Tryggestad , M Van Name , E Isganaitis

Brief summary: This analysis of data from the TODAY study examined the impact of parental diabetes on outcomes in young individuals with T2D during over 12 years of follow-up. This novel observation demonstrates that parental diabetes affects not only earlier T2D onset, but also more rapid long-term progression and more complications.Comment: This study showed that T2D diagnosis in either parent was associated with younger age at T2D diagnosis in their c...

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ey0021.12-8 | Pregnancy and Youth Onset T2D | ESPEYB21

12.8. Impact of youth onset type 2 diabetes during pregnancy on microvascular and cardiac outcomes

JB Tryggestad , KL Drews , L Mele , S Arslanian , SD Chernausek , EN Escaname , M Geffner , E Isganaitis , J Sprague , MM; TODAY Study Group. Kelsey

Brief Summary: This observational study showed that pregnancy increases the risk of hyperfiltration in women with youth-onset T2D, but not other micro or macrovascular complications.Comment: This study examined whether pregnancy exacerbates health outcomes in young women with T2D, particularly by testing for changes in the occurrence of microvascular and macrovascular complications. Previous findings showed that women in their fourth decade experience a ...

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ESPE Yearbook of Paediatric Endocrinology

10.7. Maternal diabetes in youth-onset type 2 diabetes is associated with progressive dysglycemia and risk of complications

12.8. Impact of youth onset type 2 diabetes during pregnancy on microvascular and cardiac outcomes

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