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J Clin Endocrinol Metab. 2020; 105: e373041. https://pubmed.ncbi.nlm.nih.gov/32706856/This retrospective analysis of the Pfizer International Growth Database (KIGS) included 1149 cancer survivors with growth hormone deficiency (GHD) who had received growth hormone therapy (GHT) for at least 5 years. Patients with craniopharyngioma had the best 5-year growth response ...

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ey0020.7-4 | Gonadal Function and Fertility Issues in Childhood Cancer Survivors | ESPEYB20

7.4. Reduced-intensity conditioning mitigates risk for primary ovarian insufficiency but does not decrease risk for infertility in pediatric and young adult survivors of hematopoietic stem cell transplantation

JD Bender , H Oquendo-Del Toro , J Benoit , JC Howell , P Badia , SM Davies , MS Grimley , S Jodele , C Phillips , K Burns , R Marsh , A Nelson , G Wallace , CE Dandoy , A Pate , AC Strine , O Frias , L Breech , SR Rose , H Hoefgen , P Khandelwal , KC Myers

Brief summary: This single-center, retrospective, cross-sectional study compared the prevalence of gonadal insufficiency and infertility among 58 pubertal, post pubertal and young adult survivors of hematopoietic stem cell Transplantation (HSCT), treated with conditioning regimens of different intensity.Gonadal insufficiency or infertility affects almost all HSCT survivors who received a myeloablative conditioning (MAC) regimen. In recent years, reduced-...

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ESPE Yearbook of Paediatric Endocrinology

9.12 Response to GH treatment after radiation therapy depends on location of irradiation

7.4. Reduced-intensity conditioning mitigates risk for primary ovarian insufficiency but does not decrease risk for infertility in pediatric and young adult survivors of hematopoietic stem cell transplantation

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