ISSN 1662-4009 (online)

ey0021.12-12 | Metabolic Syndrome | ESPEYB21

12.12. Association of metabolic syndrome with neuroimaging and cognitive outcomes in the UK Biobank

D Qureshi , A Topiwala , SU Al Abid , NE Allen , E Kuźma , TJ Littlejohns

Brief Summary: This observational study assessed the association between metabolic syndrome (MetS) and its components with structural neuroimaging outcomes and cognitive domains in 37,395 dementia-free adults from the UK Biobank. MetS was associated with poorer brain health, characterized by reduced brain volume, increased vascular pathology, and diminished cognitive function.Comment: MetS is characterized by the cluster of central obesity, hypertension,...