ESPE Yearbook of Paediatric Endocrinology

Introduction: Survival rates for childhood cancers have steadily improved over the past decades. These changes have shifted the concerns of parents and patients. While survival was previously the primary concern, late effects of cancer treatment are now becoming a major health issue. With a 5-year survival rate exceeding 85% for all cancers combined in this age group, many young survivors will live long enough to have biological children, but they may have concerns about the p...

PrefaceAs in previous years, most of the selected papers concern the medium and long-term complications of cancer therapy. Issues related to long-term surveillance strategies represent an emerging topic of discussion. In comparison with previous years, this year we have found few truly original and innovative studies. Rather, the attention of the researchers seems to be focused on confirming and consolidating acquired data, in particular:<p class="ab...

Introduction: As in previous years, most of the data published this year focuses on the topic of fertility preservation in childhood cancer survivors.New studies have shown that the reproductive capacity of these patients is now significantly increased compared to what was reported in previous decades. This improvement is clearly related to improved fertility preservation and assisted reproduction techniques. Another relevant factor is the progressive pe...

Preface: Survival rates of childhood cancer have been steadily improving over the past 3 decades, with 5-year overall survival now approaching 85% in Western countries. These changes have shifted parental and patients’ concerns. While survival was previously the primary concern, the late effects of cancer treatment are now becoming major healthcare issues. Epidemiological studies in childhood cancer survivors (CCS) have shown a significant decrease in male fertility when ...

...

As usual, the year in research in Oncology and chronic disease has been very rich. Most of the highlighted papers investigate the effects of cancer treatment on the endocrine system. Issues related to long-term surveillance strategies represent an emerging topic of discussion.Furthermore, a few key points about growth retardation as a common complication of different chronic systemic diseases in children have been defined:• t...

Introduction: As in previous years, most of the included papers concern the medium and long-term complications of cancer therapy. Issues related to long-term surveillance strategies represent an emerging topic of discussion. These highlighted papers have confirmed and consolidated knowledge in the following areas:– The hormone deficiencies resulting from cancer treatment are predominantly secondary to radiotherapy.– Chemo...