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ey0016.4-14 | Mechanism of the Year | ESPEYB16

4.14. IGF-2 preprograms maturing macrophages to acquire oxidative phosphorylation-dependent anti-inflammatory properties

L Du , L Lin , Q Li , K Liu , Y Huang , X Wang , K Cao , X Chen , W Cao , F Li , C Shao , Y Wang , Y Shi

To read the full abstract: Cell Metab. 2019 4;29:13631375.Mesenchymal stem and/or stromal cells (MSCs) regulate immune system and have been associated with inflammatory and autoimmune diseases. The IGF system is mainly known for its role in the regulation of growth, development and metabolism. A possible role of IGF-I in inflammation has recently been proposed [1, 2], whereas the e...

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ey0019.1-1 | Basic Science and Stem Cells | ESPEYB19

1.1. Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development

X Zhou , Y Lu , F Zhao , J Dong , W Ma , S Zhong , M Wang , B Wang , Y Zhao , Y Shi , Q Ma , T Lu , J Zhang , X Wang , Q Wu

Cell Stem Cell. 2022 Feb 3;29(2):328-343.e5. doi: 10.1016/j.stem.2021.11.009. PMID: 34879244.Brief Summary: By applying single-cell RNA sequencing (scRNA-seq) to 112,376 cells of human hypothalamus ranging from 720 gestational weeks (GW720), the authors produced a spatiotemporal transcriptome atlas of human hypothalamus development and revealed critical regulatory genes control...

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ESPE Yearbook of Paediatric Endocrinology

4.14. IGF-2 preprograms maturing macrophages to acquire oxidative phosphorylation-dependent anti-inflammatory properties

1.1. Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development

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