ey0021.3-13 | Thyroid Autoimmunity | ESPEYB21
Lafontaine Nicole
, Shore Christopher J
, Campbell Purdey J
, Mullin Benjamin H
, Brown Suzanne J
, Panicker Vijay
, Dudbridge Frank
, Brix Thomas H
, Hegedus Laszlo
, Wilson Scott G
, Bell Jordana T
, Walsh John P
Brief Summary: This epigenome-wide association study (EWAS) aimed to identify differentially methylated positions (DMPs) and regions (DMRs) between Graves disease (GD) and Hashimotos disease (HD) in two independent patient cohorts from Australia (30 patients with GD and 30 with HD, discovery cohort) and Denmark (32 patients with GD and 32 with HD, replication cohort). Linear mixed models were used to test for differences in quantile-normalized β values of DNAm...