ESPE Yearbook of Paediatric Endocrinology

Brief summary: This study analyzed cross-sectional data on almost 5,000 adolescents from the Adolescent Brain Cognitive Development (ABCD) cohort data (https://abcdstudy.org/), including resting state functional MRI, structural MRI and neurocognitive task scores. Excess BMI in young adolescents was associated with profound aberrant topological alterations in maturating functional circuits, as well as with underdeveloped brain structures that may adversely impact cogni...