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ey0015.13-15 | Advances in the Diagnosis and Management of Congenital Hypothyroidism | ESPEYB15

The five papers included in this section reflect the increasing interest by resource-limited countries in developing such a program but also highlight specific points that need to be considered in countries that embark in this wonderful initiative to make it successful.

S Gowachirapant , N Jaiswal , A Melse-Boonstra , V Galetti , S Stinca , I Mackenzie , S Thomas , T Thomas , P Winichagoon , K Srinivasan , MB Zimmerman

To read the full abstract: Lancet Diabetes Endocrinol 2017; 5:853-63 This prospective, randomized trial investigates the benefits of iodine supplementation (200 mcg per day) in pregnant women from Thailand and India on the neurological development of their children. Iodine readily crosses the placenta and is required for the synthesis of thyroid hormones by the fetal thyroid gland. In add...

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ey0015.10-21 | Prevention | ESPEYB15

10.21 Loss of intra-islet heparan sulfate is a highly sensitive marker of T1DM progression in humans

CJ Simeonovic , SK Popp , LM Starrs , DJ Brown , AF Ziolkowski , B Ludwig , SR Bornstein , JD Wilson , A Pugliese , TWH Kay , HE Thomas , T Loudovaris , FJ Choong , C Freeman , CR Parish

To read the full abstract: PLoS One. 2018;13:e0191360Up to now most studies to prevent autoimmune T1DM have focused on directly suppressing the autoimmune response rather than to better understanding the intrinsic requirements for beta cell survival. In this trial intracellular heparan sulfate was investigated as an essential requirement for the survival of beta cells and a marker for beta...

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ESPE Yearbook of Paediatric Endocrinology

The five papers included in this section reflect the increasing interest by resource-limited countries in developing such a program but also highlight specific points that need to be considered in countries that embark in this wonderful initiative to make it successful.

10.21 Loss of intra-islet heparan sulfate is a highly sensitive marker of T1DM progression in humans

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