ISSN 1662-4009 (online)

ey0021.3-6 | Thyroid Function - Genetic Determinants and Associations with Health and (Thyroid) Disease | ESPEYB21

3.6. Genetic determinants of thyroid function in children

Mulder Tessa A , Campbell Purdey J , Taylor Peter N , Peeters Robin P , Wilson Scott G , Medici Marco , Dayan Colin , Jaddoe Vincent V W , Walsh John P , Martin Nicholas G , Tiemeier Henning , Korevaar Tim I M

Brief Summary: This study investigated the genetic determinants of thyroid function in newborns and (pre)school children by analyzing the associations between single nucleotide polymorphisms (SNPs) previously identified in adults, and childhood TSH within the reference interval, and FT4 concentrations. It included three large population-based cohorts with data on genetic variants and thyroid function: Generation R (Netherlands), ALSPAC (UK), and BLTS (Australia), comprising 7,...