ESPE Yearbook of Paediatric Endocrinology

Brief Summary: This observational study assessed the association between metabolic syndrome (MetS) and its components with structural neuroimaging outcomes and cognitive domains in 37,395 dementia-free adults from the UK Biobank. MetS was associated with poorer brain health, characterized by reduced brain volume, increased vascular pathology, and diminished cognitive function.Comment: MetS is characterized by the cluster of central obesity, hypertension,...