ISSN 1662-4009 (online)

ey0021.1-12 | New Treatments and Hopes | ESPEYB21

1.12. Insights into central congenital hypothyroidism: A multicenter retrospective analysis

A German , S Almashanu , Vries L de , Margolis M Gil , R Halloun , A Haim , O Eyal , F Levy-Khademi , D Pivko-Levy , J Nir , O Pinhas-Hamiel , Y Tenenbaum-Rakover

Brief Summary: This multicentre retrospective cross-sectional study provides critical insights into the epidemiology, clinical presentation, and neurodevelopmental outcomes of central congenital hypothyroidism (CCH).CCH is a rare disorder that occurs due to insufficient hypothalamic-pituitary stimulation of the thyroid, characterized by low total T4 (TT4) with either low, normal or slightly elevated TSH. Most newborn screening (NBS) programs for CH are p...