ISSN 1662-4009 (online)

ey0016.12-11 | Lipid Metabolism | ESPEYB16

12.11. Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cells

J Sandhu , S Li , L Fairall , SG Pfisterer , JE Gurnett , X et al. Xiao

Cell. 2018; 175(2): 514–29 e20.URL: http://www.ncbi.nlm.nih.gov/pubmed/30220461Summary: The enigma of how cholesterol is transported within cells has been solved in these experimental mouse models and structural imaging studies by the discovery of the proteins Aster A, B and C, which serve as a molecular bridge for the transfer of cholesterol from the pl...