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ey0015.13-3 | How does paediatric endocrinology and diabetes fit in the global initiatives? | ESPEYB15

13.3 Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects: a cluster-randomised controlled trial

A Nsagni , D Semakula , AD Oxman , A Austvoll-Dahlgren , M Oxman , S Rosenbaum , A Morelli , C Glenton , S Lewin , M Kaseje , I Chalmers , A Fretheim , Y Ding , NK Sewankambo

To read the full abstract: Lancet 2017; 390: 374-88See comment on 13.4...

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ey0019.12-11 | Hyperlipidemia | ESPEYB19

12.11. Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial

H. Wang J, Zhao J, Yan C, Xi C, Wu C, Zhao J, Li F, Ding Y, Zhang R, Qi S, Li X, Liu C, Hou W, Chen H, Wang Y, Wu D, Chen K, Jiang H, Huang H, Liu

Cell Metabolism 2022;34(5):667-80.e6. doi: 10.1016/j.cmet.2022.03.006Brief Summary: In preclinical models and a phase 1 trial, a powerful new lipid small molecule was shown to act through a mechanism distinct from those of known hypolipidemic agents. Targeting HNF-1α may be a new therapeutic strategy.Comment: Familial hypercholesterolemia (FH) is the most common...

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ESPE Yearbook of Paediatric Endocrinology

13.3 Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects: a cluster-randomised controlled trial

12.11. Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial

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