ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

Page 1 of about 2 results

ey0018.2-19 | Maternal Obesity and Long-term Infant Consequences | ESPEYB18

2.19. Differences of DNA methylation patterns in the placenta of large for gestational age infant

Z Shen , Y Tang , Y Song , W Shen , C Zou

Medicine (Baltimore). 2020 Sep 25;99(39):e22389. doi: 10.1097/MD.0000000000022389. PMID: 32991460.In this relatively small study (6 placenta) the placentas from mothers of infants born large for gestational age (LGA) were compared to placentas of appropriate gestational age (AGA) infants for changes in genome wide DNA methylation. There were significant differences in the specific meth...
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ey0021.12-11 | Metabolic Syndrome | ESPEYB21

12.11. Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction

Y Liu , JJ Jiang , SY Du , LS Mu , JJ Fan , JC Hu , Y Ye , M Ding , WY Zhou , QH Yu , YF Xia , HY Xu , YJ Shi , SW Qian , Y Tang , W Li , YJ Dang , X Dong , XY Li , CJ Xu , QQ Tang

Brief Summary: Artemisinins, compounds known for their antimalarial properties, suppress ovarian androgen synthesis by promoting degradation of cytochrome P450 11A1 (CYP11A1). Hence, they are a promising new approach for preventing and treating PCOS.Comment: Polycystic ovary syndrome (PCOS), characterized by hyperandrogenism, chronic anovulation, and insulin resistance, is one of the most common reproductive endocrinopathies, affecting ~8-18% of reproduc...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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