ey0021.12-11 | Metabolic Syndrome | ESPEYB21
Y Liu
, JJ Jiang
, SY Du
, LS Mu
, JJ Fan
, JC Hu
, Y Ye
, M Ding
, WY Zhou
, QH Yu
, YF Xia
, HY Xu
, YJ Shi
, SW Qian
, Y Tang
, W Li
, YJ Dang
, X Dong
, XY Li
, CJ Xu
, QQ Tang
Brief Summary: Artemisinins, compounds known for their antimalarial properties, suppress ovarian androgen synthesis by promoting degradation of cytochrome P450 11A1 (CYP11A1). Hence, they are a promising new approach for preventing and treating PCOS.Comment: Polycystic ovary syndrome (PCOS), characterized by hyperandrogenism, chronic anovulation, and insulin resistance, is one of the most common reproductive endocrinopathies, affecting ~8-18% of reproduc...